| Variant | Mutation | Mut count | Country count | Continent count | First date |
|---|---|---|---|---|---|
| PQ.17.6 | S:L118I | 6 | 7 | 2 | 2025-11-13 |
| QF.2.2.1 | ORF1a:E1815K | 9 | 5 | 3 | 2025-11-13 |
| XFG.29 | ORF1b:S2198G | 4 | 2 | 2 | 2025-11-13 |
| PQ.17.7 | ORF1a:A3688V | 5 | 2 | 2 | 2025-11-14 |
| PQ.17.7 | ORF8:D63G | 5 | 2 | 2 | 2025-11-14 |
| PQ.2.1.4 | ORF8:I74V | 7 | 6 | 2 | 2025-11-14 |
| XFG.14.1.8 | N:G164V | 5 | 4 | 3 | 2025-11-14 |
| XFG.2.5 | ORF1b:R240K | 21 | 9 | 3 | 2025-11-14 |
| XFG.2.5 | ORF1b:S2292I | 21 | 9 | 3 | 2025-11-14 |
| XFG.3.4.1 | ORF3a:S26L | 4 | 3 | 2 | 2025-11-14 |
| QF.2 | ORF7a:F6L | 4 | 2 | 2 | 2025-11-15 |
| QF.5 | S:-24L | 7 | 4 | 3 | 2025-11-15 |
| QF.5 | S:-25P | 4 | 2 | 2 | 2025-11-15 |
| QF.5 | S:-26P | 6 | 3 | 2 | 2025-11-15 |
| QF.5 | S:I19T | 4 | 2 | 2 | 2025-11-15 |
| QF.5 | S:N22T | 4 | 2 | 2 | 2025-11-15 |
| QF.5 | S:S27A | 4 | 3 | 2 | 2025-11-15 |
| QF.5 | S:T21R | 4 | 2 | 2 | 2025-11-15 |
| RE.1.1 | ORF1b:H1897Y | 34 | 5 | 3 | 2025-11-15 |
| RE.1.1 | S:-211A | 50 | 4 | 4 | 2025-11-15 |
| RE.1.1 | S:I212S | 50 | 4 | 4 | 2025-11-15 |
| RE.1.1 | S:R214T | 50 | 4 | 4 | 2025-11-15 |
| RE.1.1 | S:V213D | 50 | 4 | 4 | 2025-11-15 |
| PQ.2.1 | ORF3a:S165F | 6 | 3 | 2 | 2025-11-16 |
| PQ.17 | ORF3a:G254R | 5 | 2 | 2 | 2025-11-17 |
| PQ.2.1.7 | ORF1b:I1181V | 6 | 8 | 4 | 2025-11-17 |
| QY.2 | ORF1a:P971S | 8 | 5 | 3 | 2025-11-17 |
| RE.2.2 | ORF1a:S2500F | 13 | 3 | 2 | 2025-11-17 |
| XFG.10.5 | ORF1a:G603S | 5 | 9 | 2 | 2025-11-17 |
| XFG.6.1 | S:P1263S | 5 | 4 | 4 | 2025-11-17 |
| LF.7.11.4 | ORF3a:V55I | 5 | 3 | 2 | 2025-11-18 |
| PQ.14.1 | ORF1a:G519S | 6 | 4 | 3 | 2025-11-18 |
| PQ.14.1 | ORF3a:G251C | 7 | 6 | 3 | 2025-11-18 |
| XFG.2.8.1 | ORF1b:P1682S | 4 | 4 | 2 | 2025-11-18 |
| RD.1.1 | S:-211A | 6 | 2 | 2 | 2025-11-19 |
| RD.1.1 | S:I212S | 5 | 2 | 2 | 2025-11-19 |
| RD.1.1 | S:R214T | 6 | 2 | 2 | 2025-11-19 |
| RD.1.1 | S:V213D | 6 | 2 | 2 | 2025-11-19 |
| XFG.3.16 | ORF1a:K1077N | 4 | 2 | 2 | 2025-11-19 |
| XFG.3.16 | ORF1b:K2557R | 4 | 2 | 2 | 2025-11-19 |
| XFG.3.16 | ORF6:I60T | 4 | 2 | 2 | 2025-11-19 |
| XFG.3.17 | ORF7a:I10L | 5 | 3 | 2 | 2025-11-19 |
| XFG.3.4.1 | ORF1a:G442D | 4 | 3 | 2 | 2025-11-19 |
| PQ.2.1.5 | ORF1a:A2139V | 6 | 4 | 1 | 2025-11-20 |
| XFG.37 | ORF1a:G963C | 9 | 2 | 2 | 2025-11-20 |
| XFG.37 | S:S680F | 10 | 4 | 2 | 2025-11-20 |
| XFG.5.4 | ORF1a:D211A | 5 | 2 | 2 | 2025-11-21 |
| XFG.5.4 | ORF1a:T1022I | 4 | 2 | 2 | 2025-11-21 |
| BA.3.2.2 | ORF8:-120F | 4 | 3 | 2 | 2025-11-23 |
| RE.2 | N:N126K | 11 | 2 | 2 | 2025-11-24 |
| RE.2 | S:-211A | 4 | 3 | 2 | 2025-11-24 |
| RE.2 | S:I212S | 4 | 3 | 2 | 2025-11-24 |
| RE.2 | S:R214T | 4 | 3 | 2 | 2025-11-24 |
| RE.2 | S:V213D | 4 | 3 | 2 | 2025-11-24 |
| RE.2.1 | ORF3a:I63T | 15 | 4 | 1 | 2025-11-24 |
| PQ.17.7.1 | ORF1a:P1810L | 17 | 2 | 2 | 2025-11-25 |
| PQ.2.1.4 | S:A522P | 4 | 3 | 3 | 2025-11-25 |
| QY.2 | ORF1a:S531C | 4 | 4 | 2 | 2025-11-25 |
| RE.1.1 | S:H49Y | 4 | 2 | 2 | 2025-11-25 |
| XFG.1.1.1 | ORF1b:P160S | 6 | 2 | 2 | 2025-11-25 |
| XFG.9 | S:R182K | 5 | 2 | 2 | 2025-11-26 |
| XFG.3.4.1 | ORF1a:A2554V | 5 | 2 | 2 | 2025-11-27 |
| XFZ.1 | ORF1b:L1504F | 6 | 2 | 2 | 2025-11-27 |
| XFZ.1 | ORF3a:Y215F | 6 | 2 | 2 | 2025-11-27 |
| QQ.2 | ORF1a:E743D | 5 | 4 | 1 | 2025-11-28 |
| PQ.17 | S:S680F | 6 | 5 | 3 | 2025-11-30 |
| XFG.3.15 | ORF7a:L96F | 4 | 4 | 2 | 2025-11-30 |
| XFG.3.4.1 | ORF1b:P2256S | 5 | 2 | 2 | 2025-11-30 |
| RE.2 | ORF1b:T1896I | 6 | 2 | 2 | 2025-12-01 |
| PQ.14.3 | S:K679R | 5 | 3 | 2 | 2025-12-02 |
| QY.2 | ORF1a:P1640L | 7 | 6 | 4 | 2025-12-03 |
| XFG.2.5 | ORF3a:A110S | 6 | 2 | 2 | 2025-12-04 |
| RE.1.1 | S:P1162L | 4 | 2 | 2 | 2025-12-09 |
| XGA.2 | ORF1a:D2299E | 4 | 4 | 2 | 2025-12-17 |