| Variant | Mutation | Mut count | Country count | Continent count | First date |
|---|---|---|---|---|---|
| PQ.2.1 | ORF1a:T224I | 4 | 2 | 2 | 2025-09-27 |
| QF.1.1 | S:N658S | 9 | 3 | 2 | 2025-09-27 |
| XFG.3 | ORF1b:N1591D | 7 | 2 | 2 | 2025-09-27 |
| XFG.8.2 | ORF1a:F1867L | 4 | 2 | 2 | 2025-09-27 |
| XFG.8.2 | ORF1a:V596L | 4 | 2 | 2 | 2025-09-27 |
| PQ.2 | ORF1a:S4286N | 5 | 3 | 2 | 2025-09-28 |
| XFG.14.1.3 | ORF1a:N2065S | 5 | 2 | 2 | 2025-09-28 |
| XFG.3.4 | ORF1b:D131Y | 4 | 3 | 2 | 2025-09-28 |
| XFG.6 | S:R681H | 6 | 4 | 1 | 2025-09-28 |
| PQ.2.1 | ORF3a:T89I | 5 | 3 | 3 | 2025-09-29 |
| QT.1 | N:S37P | 7 | 4 | 2 | 2025-09-29 |
| XFG.3 | S:P812S | 4 | 3 | 2 | 2025-09-29 |
| XFG.3.2 | ORF1a:A239V | 6 | 2 | 2 | 2025-09-29 |
| XFG.3.2 | ORF1a:T1597I | 5 | 2 | 2 | 2025-09-29 |
| XFG.3.2 | ORF1a:V2588I | 5 | 2 | 2 | 2025-09-29 |
| XFG.4 | N:M322I | 10 | 2 | 2 | 2025-09-29 |
| XFV | ORF7a:T39I | 4 | 3 | 2 | 2025-09-29 |
| PQ.2.1 | ORF3a:L140F | 5 | 2 | 2 | 2025-09-30 |
| XFG.14.1 | ORF1b:T132I | 4 | 2 | 2 | 2025-09-30 |
| XFG.3 | ORF1a:L469F | 5 | 3 | 2 | 2025-09-30 |
| XFG.5.2.1 | ORF1b:S1182L | 4 | 2 | 2 | 2025-09-30 |
| XFG.9.3 | ORF1a:R2159W | 4 | 2 | 2 | 2025-09-30 |
| XFG | ORF3a:R6K | 4 | 3 | 2 | 2025-10-01 |
| XFG.2 | S:E1188D | 6 | 2 | 2 | 2025-10-01 |
| XFG.4 | S:A376T | 5 | 2 | 2 | 2025-10-01 |
| NB.1.8.1 | ORF1a:D2980G | 4 | 3 | 2 | 2025-10-03 |
| XFG.3.4.1 | ORF1a:T1241I | 4 | 2 | 2 | 2025-10-03 |
| PQ.2.1 | ORF7a:A66V | 12 | 3 | 2 | 2025-10-04 |
| XFG.14.1.1 | M:A30T | 4 | 2 | 2 | 2025-10-05 |
| XFG.3.4.1 | ORF1a:F3027L | 4 | 2 | 2 | 2025-10-05 |
| XFG.6.2 | S:I1216V | 6 | 3 | 2 | 2025-10-05 |
| XFG.6.2 | S:S151N | 5 | 3 | 2 | 2025-10-05 |
| PQ.4.1 | S:R346T | 6 | 3 | 2 | 2025-10-06 |
| XFG.14.1 | ORF1a:F3027L | 9 | 2 | 2 | 2025-10-06 |
| XFG.6.4 | ORF1a:S1857L | 6 | 4 | 1 | 2025-10-06 |
| NB.1.8.1 | ORF1a:V3560I | 4 | 2 | 2 | 2025-10-07 |
| PQ.14 | ORF7b:W29R | 6 | 3 | 2 | 2025-10-07 |
| PQ.2.5 | ORF1a:T2495I | 9 | 2 | 2 | 2025-10-07 |
| XFG.14.1 | ORF1a:T2274I | 4 | 2 | 2 | 2025-10-07 |
| XFG.3.16 | ORF1a:M2259I | 5 | 2 | 2 | 2025-10-07 |
| XFG.5.1 | ORF3a:L53F | 4 | 3 | 2 | 2025-10-07 |
| PQ.2.4.2 | N:T135I | 5 | 2 | 2 | 2025-10-08 |
| PQ.2.4.2 | ORF1a:A2080V | 5 | 2 | 2 | 2025-10-08 |
| PQ.2.9 | ORF1b:A1918V | 10 | 2 | 2 | 2025-10-08 |
| XFG.6 | ORF1b:R188Q | 6 | 3 | 2 | 2025-10-08 |
| XFG.6.10 | ORF1a:K3353R | 8 | 4 | 3 | 2025-10-08 |
| PQ.2.1 | ORF1a:A2618N | 4 | 2 | 2 | 2025-10-09 |
| PQ.2.1 | ORF1a:A2891T | 4 | 2 | 2 | 2025-10-09 |
| XFG.6.2 | ORF1b:K2209E | 4 | 3 | 2 | 2025-10-10 |
| XFG.1.1 | S:I212L | 4 | 2 | 2 | 2025-10-11 |
| QF.5 | ORF1a:D203N | 7 | 6 | 2 | 2025-10-13 |
| XFG.5.2 | ORF8:I71T | 6 | 2 | 2 | 2025-10-13 |
| XFG.5.2 | S:A845S | 5 | 2 | 2 | 2025-10-13 |
| XFG.3.10 | S:S680F | 4 | 4 | 2 | 2025-10-14 |
| XFG.5.1 | S:I1114T | 10 | 2 | 2 | 2025-10-14 |
| XFG.17.2.1 | ORF1b:L314F | 4 | 2 | 2 | 2025-10-27 |
| XFG.14.1 | ORF1b:T239I | 4 | 2 | 2 | 2025-10-28 |
| XFG.14.1 | N:G164V | 11 | 3 | 3 | 2025-11-03 |