| Variant | Mutation | Mut count | Country count | Continent count | First date |
|---|---|---|---|---|---|
| QF.3 | S:-25P | 11 | 2 | 2 | 2025-10-18 |
| QF.3 | S:I19T | 11 | 2 | 2 | 2025-10-18 |
| QF.3 | S:N22T | 11 | 2 | 2 | 2025-10-18 |
| QF.3 | S:T21R | 11 | 2 | 2 | 2025-10-18 |
| PQ.4.6 | ORF1a:T1638N | 7 | 7 | 2 | 2025-10-20 |
| PQ.4.6 | ORF8:G8* | 7 | 7 | 2 | 2025-10-20 |
| XFG.3.31 | ORF1a:P361L | 7 | 10 | 2 | 2025-10-20 |
| XFG.26 | ORF1a:S558P | 11 | 2 | 2 | 2025-10-21 |
| XFG.26 | ORF1a:V2783F | 11 | 2 | 2 | 2025-10-21 |
| QF.2 | ORF1a:P885S | 16 | 2 | 2 | 2025-10-22 |
| XFG.3.19 | S:N148D | 5 | 3 | 2 | 2025-10-22 |
| XFG.3.4.6 | ORF8:P93L | 4 | 2 | 2 | 2025-10-22 |
| XFG | ORF1a:T4087I | 4 | 2 | 2 | 2025-10-24 |
| QM.1 | ORF1a:P1158S | 4 | 2 | 2 | 2025-10-26 |
| XFG.17.2.1 | S:K440R | 5 | 3 | 2 | 2025-10-26 |
| XFG.17.2.1 | ORF1b:L314F | 4 | 2 | 2 | 2025-10-27 |
| PQ.2.1 | ORF1a:I3779T | 5 | 3 | 3 | 2025-10-28 |
| PQ.2.1 | ORF1a:T3461A | 4 | 2 | 2 | 2025-10-28 |
| PQ.2.1 | ORF1a:T350I | 4 | 2 | 2 | 2025-10-28 |
| PQ.2.1 | ORF1b:I958T | 4 | 2 | 2 | 2025-10-28 |
| PQ.2.1 | ORF1b:S2430G | 4 | 2 | 2 | 2025-10-28 |
| XFC.1 | S:K478E | 12 | 15 | 5 | 2025-10-28 |
| XFG.14.1 | ORF1b:T239I | 4 | 2 | 2 | 2025-10-28 |
| XFG | ORF1a:V779I | 12 | 2 | 2 | 2025-10-29 |
| XFG.17.2.1 | ORF1b:T132I | 4 | 2 | 2 | 2025-10-29 |
| PQ.17.7.2 | S:D420N | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:-24L | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:-25P | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:-26P | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:I19T | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:N22T | 6 | 3 | 2 | 2025-10-30 |
| XFG.3.1.3 | S:T21R | 6 | 3 | 2 | 2025-10-30 |
| XFG.23.1.3 | S:S446N | 4 | 3 | 2 | 2025-11-02 |
| XFG.14.1 | N:G164V | 16 | 4 | 3 | 2025-11-03 |
| XFG.1.1.1 | S:D1146G | 5 | 7 | 2 | 2025-11-04 |
| XFG.3.15 | ORF1a:I3758V | 4 | 2 | 2 | 2025-11-04 |
| PQ.25.2 | ORF1b:S1570P | 5 | 2 | 2 | 2025-11-05 |
| XFG.2.6 | ORF1a:T1638I | 6 | 12 | 4 | 2025-11-05 |
| XFG.3 | ORF3a:T14I | 5 | 3 | 2 | 2025-11-05 |
| RE.2.1 | S:-211A | 7 | 4 | 1 | 2025-11-06 |
| RE.2.1 | S:I212S | 7 | 4 | 1 | 2025-11-06 |
| RE.2.1 | S:R214T | 7 | 4 | 1 | 2025-11-06 |
| RE.2.1 | S:V213D | 7 | 4 | 1 | 2025-11-06 |
| RE.2.2 | N:A173V | 32 | 4 | 1 | 2025-11-06 |
| XFG.5.1 | ORF8:Q91R | 11 | 2 | 2 | 2025-11-07 |
| PQ.4.6 | S:K150N | 5 | 3 | 2 | 2025-11-09 |
| PQ.17.7 | ORF1a:A3688V | 4 | 2 | 2 | 2025-11-14 |
| PQ.17.7 | ORF8:D63G | 4 | 2 | 2 | 2025-11-14 |
| XFG.2.5 | ORF1b:R240K | 12 | 8 | 3 | 2025-11-14 |
| XFG.2.5 | ORF1b:S2292I | 12 | 8 | 3 | 2025-11-14 |
| RE.1.1 | ORF1b:H1897Y | 9 | 2 | 2 | 2025-11-15 |
| RE.1.1 | S:-211A | 10 | 2 | 2 | 2025-11-15 |
| RE.1.1 | S:I212S | 10 | 2 | 2 | 2025-11-15 |
| RE.1.1 | S:R214T | 10 | 2 | 2 | 2025-11-15 |
| RE.1.1 | S:V213D | 10 | 2 | 2 | 2025-11-15 |
| PQ.17 | ORF3a:G254R | 5 | 2 | 2 | 2025-11-17 |
| LF.7.11.4 | ORF3a:V55I | 5 | 3 | 2 | 2025-11-18 |
| XFG.5.4 | ORF1a:D211A | 5 | 2 | 2 | 2025-11-21 |
| XFG.5.4 | ORF1a:T1022I | 4 | 2 | 2 | 2025-11-21 |
| XFG.9 | S:R182K | 4 | 2 | 2 | 2025-11-26 |